Napoli Clash with Chelsea: Bold Predictions, Key Lineups and What to Expect
Both Napoli and Chelsea face a crucial encounter on the Champions League's final matchday, each carrying distinct objectives into this decisive clash.
Napoli's goal is simply to prolong their European journey by securing a top-24 finish—sufficient for playoff qualification—while Chelsea currently sit in an automatic round of 16 berth.
This matchup holds special meaning for the visiting team, whose previous trip to the Stadio Diego Armando Maradona came during their extraordinary 2011–12 Champions League triumph. That campaign featured an unforgettable comeback from a 3–1 first-leg deficit, completed in extra time at Stamford Bridge in one of the club's most iconic European moments.
The Italian side, previously managed by Walter Mazzarri, has found it challenging to make their mark in elite European competition over recent years, despite claiming a pair of Serie A titles, and these difficulties have predictably persisted under ex-Chelsea manager Antonio Conte this term.
Last week's 1–1 stalemate against Copenhagen has left them in 25th position, just outside playoff contention. Liam Rosenior's squad, currently in eighth place, should secure their round of 16 passage with victory in southern Italy.
What Time Does Napoli vs. Chelsea Kick Off?
What Time Does Napoli vs. Chelsea Kick Off?
Napoli vs. Chelsea Head-to-Head Record (All Games)
Napoli vs. Chelsea Head-to-Head Record (All Games)
Current Form (All Competitions)
Current Form (All Competitions)
Napoli (LDWDD) | Chelsea (WWWDW) |
|---|---|
Juventus 3–0 Napoli | Crystal Palace 1–3 Chelsea |
Copenhagen 1–1 Napoli | Chelsea 1–0 Pafos |
Napoli 1–0 Sassuolo | Chelsea 2–0 Brentford |
Napoli 0–0 Parma | Chelsea 2–3 Arsenal |
Napoli 2–2 Inter | Charlton 1–5 Chelsea |
How to Watch Napoli vs. Chelsea on TV, Live Stream
How to Watch Napoli vs. Chelsea on TV, Live Stream
Country | TV channel/live stream |
|---|---|
United Kingdom | TNT Sports 4, discovery+, discovery+ App |
United States | Paramount+ |
Canada | DAZN Canada, fuboTV Canada |
Mexico | Max Mexico, Space Mexico |
Napoli Team News
Napoli Team News

Napoli face severe squad limitations. Although Conte has recently regained Romelu Lukaku following an extended injury layoff, Wednesday's hosts confront an extensive injury list.
Notable absentees include Kevin De Bruyne and Billy Gilmour, both former west London players. David Neres and Vanja Milinković-Savić represent additional worries for Conte, with the Brazilian winger, who had been enjoying a revival, sidelined indefinitely following surgical intervention.
Matteo Politano, Amir Rrahmani and André-Frank Zambo Anguissa will also be unavailable for the hosts in this critical encounter.
Napoli Predicted Lineup vs. Chelsea
Napoli Predicted Lineup vs. Chelsea

Napoli predicted lineup vs. Chelsea (3-4-2-1): Meret; Di Lorezno, Buongiorno, Juan; Gutierrez, Lobotka, McTominay, Oliveira; Spinazzola, Elmas; Højlund.
Chelsea Team News
Chelsea Team News

Cole Palmer has been managing a persistent groin problem throughout the campaign, though the England star sat out Chelsea's last two fixtures due to a separate thigh complaint. Nevertheless, he has participated in training before Wednesday's vital fixture and is expected to make the trip to Naples.
Whether Rosenior chooses to restore him to the starting eleven remains uncertain, particularly following his team's excellent display at Selhurst Park on Sunday.
The Blues will also be missing Dário Essugo, Tosin Adarabioyo, Levi Colwill and Roméo Lavia for Wednesday evening's match. Backup keeper Filip Jørgensen is questionable with an injury concern.
Chelsea Predicted Lineup vs. Napoli
Chelsea Predicted Lineup vs. Napoli

Chelsea predicted lineup vs. Napoli (4-2-3-1): Sánchez; James, Fofana, Chalobah, Cucurella; Caicedo, Santos; Estêvão, Fernández, Garnacho; Pedro.
Napoli vs. Chelsea Score Prediction
Napoli vs. Chelsea Score Prediction
Sunday's triumph at Crystal Palace marked the most impressive display under Rosenior's leadership to date, and the Chelsea manager will earn significant praise from the Blues supporters if he prevails against two former west London adversaries in Conte and Lukaku.
Napoli are severely weakened and operating on limited resources. They'll need to conjure something extraordinary to secure the victory they require, with Scott McTominay likely needing to deliver another standout performance.
Chelsea should enter as favorites, though the Italian champions possess resilience and could battle their way to a potentially meaningless draw. Such a result would eliminate Conte's team and further tarnish the Italian's Champions League reputation, but would also derail the Blues' round of 16 ambitions.