Sevilla Clash with Barcelona: Bold Predictions, Key Lineups, and What to Expect

Sevilla Clash with Barcelona: Bold Predictions, Key Lineups, and What to Expect

Barcelona's next challenge takes them southward to meet Sevilla in what will be their concluding fixture ahead of the October international pause.

The Catalan giants claimed the La Liga summit last weekend following their victory over Real Sociedad, though the atmosphere surrounding the team quickly soured after experiencing their maiden loss of the campaign against PSG in their most recent outing.

Hansi Flick's squad will aim to bounce back against a Sevilla team that has shown improvement recently. Matías Almeyda has performed admirably since assuming managerial duties, and following a disappointing 2024–25 campaign, Sevilla enters the weekend positioned ninth and seeking their inaugural home victory of the season.

Barcelona's last La Liga defeat at the Estadio Ramón Sánchez Pizjuán dates back more than ten years, yet the home side will be eager to break that sequence and inflict consecutive losses on Barcelona for the first time in 2025.

Here's Sports Illustrated's comprehensive match preview.

What Time Does Sevilla vs. Barcelona Kick-Off?

Sevilla vs. Barcelona Head-to-Head Record (Last Five Games)

Current Form (All Competitions)

Sevilla

Barcelona

Rayo Vallecano 0–1 Sevilla - 9/28/25

Barcelona 1–2 PSG - 10/1/25

Sevilla 1–2 Villarreal - 9/23/25

Barcelona 2–1 Real Sociedad - 9/28/25

Deportivo Alavés 1–2 Sevilla - 6/20/25

Real Oviedo 1–3 Barcelona - 9/25/25

Sevilla 2–2 Elche - 9/12/25

Barcelona 3–0 Getafe - 9/21/25

Girona 0–2 Sevilla - 8/30/25

Newcastle United 1–2 Barcelona - 9/18/25

How to Watch Sevilla vs. Barcelona on TV, Live Stream

Country

TV / Live Stream

United States

ESPN+, ESPN App, ESPN Deportes, fuboTV

United Kingdom

Premier Sports 2, Premier Sports Player, Amazon Prime Video

Canada

TSN 3, TSN+, Amazon Prime Video

Mexico

Sky Sports, Sky+

Sevilla Team News

Alexis Sanchez

Sevilla has utilized a three-center-back formation throughout this campaign and this tactical approach is expected to continue against Barcelona, with experienced defender César Azpilicueta anchoring the backline.

Alfon González and Tanguy Nianzou will remain sidelined due to injuries and may be accompanied by Joan Jordan and Adnan Januzaj, whose availability for this encounter remains doubtful.

Alexis Sánchez is expected to feature in attack against his previous employers, alongside Swiss winger Ruben Vargas and top scorer Isaac Romero leading the forward line.

Sevilla Predicted Lineup vs. Barcelona

Sevilla

Sevilla Predicted Lineup vs. Barcelona (3-4-3): Vlachodimos; Azpilicueta, Lopez, Marcao; Carmona, Agoumé, Mendy, Suazo; Sánchez, Romero, Vargas.

Barcelona Team News

Lamine Yamal Barcelona

Barcelona will miss Lamine Yamal for their fourth La Liga match this season, as the young talent continues to battle a persistent groin problem.

Yamal is joined by Gavi, Fermín López, Joan García and Raphinha among the players who won't travel to Sevilla. Conversely, Alejandro Balde has returned to full fitness and could earn his first starting role in over a month.

Several players displayed obvious signs of exhaustion against Paris Saint-Germain. It would be understandable if Flick grants Pedri some respite given the midfielder has featured in every match this season. Marcus Rashford is another candidate who might benefit from rotation.

Robert Lewandowski could return to the starting eleven, along with Marc Casadó.

Barcelona Predicted Lineup vs. Sevilla

Barcelona Predicted Lineup vs. PSG (4-2-3-1): Szczęsny; Koundé, Araújo, Cubarsí, Balde; De Jong, Casadó; Bardghji, Olmo, Torres; Lewandowski.

Sevilla vs. Barcelona Score Prediction

Although Barcelona has maintained recent superiority over Sevilla, this encounter could prove more competitive than anticipated.

Flick's team has been tested to their limits in nearly every away fixture this season, and with a fatigued squad coming off an demanding European midweek clash, the journey to Sevilla presents all the ingredients for a potential surprise result.

Nevertheless, there remains a noticeable quality difference between the two teams. The Catalans should manage to work their way through the contest and secure a hard-fought win to enter the international break atop La Liga.

Prediction: Sevilla 1–2 Barcelona